Published Work

The Fruits of Our Labor

Effect of induced dNTP pool imbalance on HIV-1 reverse transcription in macrophages.

Shepard C, Xu J, Holler J, Kim DH, Mansky LM, Schinazi RF, Kim B.
Retrovirology. 2019 Oct 26;16(1):29. doi: 10.1186/s12977-019-0491-0.
PMID: 31655617

Distinct dual antiviral mechanism that enhances hepatitis B virus mutagenesis and reduces viral DNA synthesis.

McDaniel YZ, Patterson SE, Mansky LM.
Antiviral Res. 2019 Oct;170:104540. doi: 10.1016/j.antiviral.2019.104540. Epub 2019 Jun 25.
PMID: 31247245

​​​​​​​Correction to: The Retrovirus Capsid Core

Zhang W, Mendonça LM, Mansky LM.
Subcell Biochem. 2018;88:E1. doi: 10.1007/978-981-10-8456-0_18.
PMID: 30488398

Human T-cell leukemia virus type 1 Gag domains have distinct RNA-binding specificities with implications for RNA packaging and dimerization.

Wu W, Hatterschide J, Syu YC, Cantara WA, Blower RJ, Hanson HM, Mansky LM, Musier-Forsyth K.
J Biol Chem. 2018 Oct 19;293(42):16261-16276. doi: 10.1074/jbc.RA118.005531. Epub 2018 Sep 14.
PMID: 30217825

Distinct Pathway of Human T-Cell Leukemia Virus Type 1 Gag Punctum Biogenesis Provides New Insights into Enveloped Virus Assembly.

Eichorst JP, Chen Y, Mueller JD, Mansky LM.
MBio. 2018 Sep 4;9(5). pii: e00758-18. doi: 10.1128/mBio.00758-18.
PMID: 30181245

The HIV-1 Reverse Transcriptase A62V Mutation Influences Replication Fidelity and Viral Fitness in the Context of Multi-Drug-Resistant Mutations.

Maldonado JO, Mansky LM.
Viruses. 2018 Jul 19;10(7). pii: E376. doi: 10.3390/v10070376.
PMID: 30029500

The Retrovirus Capsid Core.

Zhang W, Mendonça LM, Mansky LM.
Subcell Biochem. 2018;88:169-187. doi: 10.1007/978-981-10-8456-0_8. Review. Erratum in: Subcell Biochem. 2018;88:E1.
PMID: 29900497

 

Critical Role of the Human T-Cell Leukemia Virus Type 1 Capsid N-Terminal Domain for Gag-Gag Interactions and Virus Particle Assembly.

Martin JL, Mendonça LM, Marusinec R, Zuczek J, Angert I, Blower RJ, Mueller JD, Perilla JR, Zhang W, Mansky LM.
J Virol. 2018 Jun 29;92(14). pii: e00333-18. doi: 10.1128/JVI.00333-18. Print 2018 Jul 15.
PMID: 29695435

Perturbation of Human T-Cell Leukemia Virus Type 1 Particle Morphology by Differential Gag Co-Packaging.

Maldonado JO, Angert I, Cao S, Berk S, Zhang W, Mueller JD, Mansky LM.
Viruses. 2017 Jul 19;9(7). pii: E191. doi: 10.3390/v9070191.
PMID: 28753950

Polymorphic Nature of Human T-Cell Leukemia Virus Type 1 Particle Cores as Revealed through Characterization of a Chronically Infected Cell Line.

Meissner ME, Mendonça LM, Zhang W, Mansky LM.
J Virol. 2017 Jul 27;91(16). pii: e00369-17. doi: 10.1128/JVI.00369-17. Print 2017 Aug 15.
PMID: 28615198

Single-Strand Consensus Sequencing Reveals that HIV Type but not Subtype Significantly Impacts Viral Mutation Frequencies and Spectra.

Rawson JMO, Gohl DM, Landman SR, Roth ME, Meissner ME, Peterson TS, Hodges JS, Beckman KB, Mansky LM.
J Mol Biol. 2017 Jul 21;429(15):2290-2307. doi: 10.1016/j.jmb.2017.05.010. Epub 2017 May 11.
PMID: 28502791

 

Disparate Contributions of Human Retrovirus Capsid Subdomains to Gag-Gag Oligomerization, Virus Morphology, and Particle Biogenesis.

Martin JL, Mendonça LM, Angert I, Mueller JD, Zhang W, Mansky LM.
J Virol. 2017 Jun 26;91(14). pii: e00298-17. doi: 10.1128/JVI.00298-17. Print 2017 Jul 15.
PMID: 28446667

 

Distinct Particle Morphologies Revealed through Comparative Parallel Analyses of Retrovirus-Like Particles.

Martin JL, Cao S, Maldonado JO, Zhang W, Mansky LM.
J Virol. 2016 Aug 26;90(18):8074-84. doi: 10.1128/JVI.00666-16. Print 2016 Sep 15.
PMID: 27356903

 

Distinct Morphology of Human T-Cell Leukemia Virus Type 1-Like Particles.

Maldonado JO, Cao S, Zhang W, Mansky LM.
Viruses. 2016 May 11;8(5). pii: E132. doi: 10.3390/v8050132.
PMID: 27187442

Synergistic reduction of HIV-1 infectivity by 5-azacytidine and inhibitors of ribonucleotide reductase.

Rawson JM, Roth ME, Xie J, Daly MB, Clouser CL, Landman SR, Reilly CS, Bonnac L, Kim B, Patterson SE, Mansky LM.
Bioorg Med Chem. 2016 Jun 1;24(11):2410-22. doi: 10.1016/j.bmc.2016.03.052. Epub 2016 Mar 30.
PMID: 27117260

Dual anti-HIV mechanism of clofarabine.

Daly MB, Roth ME, Bonnac L, Maldonado JO, Xie J, Clouser CL, Patterson SE, Kim B, Mansky LM.
Retrovirology. 2016 Mar 24;13:20. doi: 10.1186/s12977-016-0254-0.
PMID: 27009333

5-Azacytidine Enhances the Mutagenesis of HIV-1 by Reduction to 5-Aza-2'-Deoxycytidine.

Rawson JM, Daly MB, Xie J, Clouser CL, Landman SR, Reilly CS, Bonnac L, Kim B, Patterson SE, Mansky LM.
Antimicrob Agents Chemother. 2016 Mar 25;60(4):2318-25. doi: 10.1128/AAC.03084-15. Print 2016 Apr.
PMID: 26833151

Molecular Studies of HTLV-1 Replication: An Update.

Martin JL, Maldonado JO, Mueller JD, Zhang W, Mansky LM.
Viruses. 2016 Jan 27;8(2). pii: E31. doi: 10.3390/v8020031. Review.
PMID: 26828513

Rapid Determination of HIV-1 Mutant Frequencies and Mutation Spectra Using an mCherry/EGFP Dual-Reporter Viral Vector.

Rawson JM, Clouser CL, Mansky LM.
Methods Mol Biol. 2016;1354:71-88. doi: 10.1007/978-1-4939-3046-3_6.
PMID: 26714706

Morphology and ultrastructure of retrovirus particles.

Zhang W, Cao S, Martin JL, Mueller JD, Mansky LM.
AIMS Biophys. 2015;2(3):343-369. Epub 2015 Aug 18.
PMID: 26448965